What is Bisabolol?

Bisabolol (α-Bisabolol)

Overview

Bisabolol is a gentle, floral terpene with soft notes of chamomile, honey, and white tea. It is best known as the primary active compound in chamomile (Matricaria chamomilla) and is valued for its soothing and restorative properties. Though found in cannabis in low concentrations, Bisabolol can have a notable calming and anti-inflammatory impact even in microdoses.

Best Suited For

• Deep relaxation and emotional recovery

• Post-stress restoration

• Topical and skincare formulations (creams, balms, oils)

• Soft, calming strain profiles

• Sensitive individuals — both mentally and physically

Effects

• Soothing and calming effect on mind and body

• Reduces anxiety and stress response

• Supports sleep quality without sedation

• Softens THC’s psychoactive sharpness

• Demonstrates anti-inflammatory and antibacterial potential

Mechanism of Action

• Modulates GABA-A receptors — promoting relaxation and calm

• Suppresses pro-inflammatory mediators in tissue response

• Enhances synergy and absorption of other active compounds

• Penetrates skin and mucosal barriers effectively

Therapeutic Research Focus

• Anxiety, fatigue, and stress-related conditions

• Insomnia and restless states

• Inflammatory or irritated skin

• Mild local analgesic effect in topical use

• Recovery after psychoactive overstimulation or nervous exhaustion

OG Lab Strains Containing Bisabolol

• Avto Tune CBD

• Lemon Sorbet

• Super Boof (trace levels)

Synergy (Entourage Effect)

• Bisabolol + Linalool — Deep relaxation and sleep synergy

• Bisabolol + Myrcene — Physical calm and evening tranquility

• Bisabolol + CBD — Recovery, softening, and skin-level balance

Bisabolol is the terpene of tenderness — quiet, restorative, and grounding, helping both mind and body find rest.