What is Limonene?

Limonene (D-Limonene)

Overview

Limonene is a citrus-scented terpene found abundantly in cannabis and throughout nature. It produces a bright, uplifting aroma reminiscent of lemons, oranges, and limes, and also occurs in citrus peels, mint, rosemary, and juniper.

It is one of the most common monoterpenes and plays a key role in shaping energetic, mood-elevating profiles of many cultivars.

Best Suited For

• Mood elevation and positive emotional tone

• Focus and motivation

• Daytime anxiety relief

• Anti-inflammatory support

• Strains with cheerful or social characteristics

Effects

• Antidepressant and anxiolytic (in small amounts)

• Promotes alertness and focus

• Enhances motivation and activity

• May reduce stomach acidity

• Contributes to a sense of lightness and sociability

Mechanism of Action

• Modulates dopaminergic and serotonergic systems

• Interacts with TRPV1 and CB1 receptors

• Enhances neuroplasticity and promotes BDNF expression

• Can amplify THC activity through receptor modulation

Therapeutic Research Focus

• Symptoms of depression and anxiety

• Fatigue and reduced tone

• Inflammatory conditions

• Gastroesophageal reflux (GERD)

• Motivational deficits linked to depressive states

OG Lab Strains Containing Limonene

• Pineapple Express

• Tropicana Cherry

Synergy (Entourage Effect)

• Limonene + Linalool — Mood stabilization with gentle relaxation

• Limonene + THC — Enhanced euphoria and sociability

• Limonene + Caryophyllene — Antidepressant and anti-inflammatory synergy

Limonene acts as a brightening agent for both mood and physiology — energizing without agitation.