What is Nerolidol?

Uncover the secrets of Nerolidol, a terpene that promotes relaxation and enhances cannabinoid absorption.

Master GrowerOctober 29, 2025
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TL;DR | Quick Summary
Nerolidol is a terpene with a woody, fruity aroma, promoting relaxation and sedation, often used in sleep and recovery formulations. It enhances the absorption of cannabinoids like CBD and THC through the skin, interacts with serotonin receptors, and has potential therapeutic benefits for stress, sleep disturbances, and skin conditions. OG Lab offers strains like Super Boof that contain Nerolidol.

Nerolidol (also known as Peruviol)

Overview

Nerolidol is a woody, fruity, and floral terpene with subtle notes of apple, hay, bark, and blossom. It produces a calming, β€œslowing” effect often associated with deep relaxation and rest. Found naturally in ginger, jasmine, tea tree, and laurel, it is also known as a transdermal enhancer β€” improving the absorption of active compounds through the skin.


Best Suited For

  • Relaxation, rest, and nighttime formulations

  • Recovery-focused or sleep-oriented blends

  • Emotional and sensory slowdown after stress

  • Topical or cosmetic applications (creams, balms, oils)


Effects

  • Deep physical and mental relaxation

  • Sedative and sleep-inducing properties

  • Reduces anxiety and tension

  • Soothes skin irritation and inflammation

  • Enhances cannabinoid absorption through skin and mucosa


Mechanism of Action

  • Interacts with GABA-A and serotonin receptors

  • Enhances CBD and THC bioavailability via transdermal absorption

  • May reduce central nervous system activity and relax smooth muscles

  • Exhibits antimicrobial and antioxidant effects


Therapeutic Research Focus

  • Insomnia and sleep disturbances

  • Stress, anxiety, and overexertion

  • Adjunct compound in CBD-based formulas

  • Skin inflammation, itching, and irritation

  • Aromatherapeutic support for relaxation


OG Lab Strains Containing Nerolidol

  • Super Boof

  • CBD Avto Tune


Synergy (Entourage Effect)

  • Nerolidol + Linalool β€” Deep sedation and anxiolytic synergy

  • Nerolidol + Myrcene β€” Physical grounding, full-body calm

  • Nerolidol + CBD β€” Enhanced absorption in topical and tincture formulations

Nerolidol is the terpene of deep rest β€” soft, grounding, and restorative, helping the body and mind to fully release.

βœ“

Quick Answer

Nerolidol is a terpene with calming effects, found in cannabis strains and useful for relaxation and enhanced absorption of cannabinoids.

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