Immunomodulation

Discover how cannabis modulates immune health, impacting inflammation and autoimmune responses.

Master GrowerNovember 25, 2025
TL;DR | Quick Summary
Cannabis influences immune health by modulating inflammation, cytokines, and the endocannabinoid system. This is significant for autoimmune conditions, chronic inflammation, and anxiety-related immune responses. Terpenes like caryophyllene and cannabinoids like CBD play crucial roles in this process. OG Lab offers strains tailored for immune support, such as AC/DC CBD and Banana Hammock RBX1.

Immunomodulation

Cannabis does not β€œboost” the immune system directly. It regulates immune reactivity by reducing excessive inflammation, modulating cytokines, and balancing the endocannabinoid system.

This effect is relevant in autoimmune conditions, allergies, chronic inflammation, PMS, and anxiety-related immune responses.


Associated terpenes

  • Caryophyllene – regulates immune response via CB2

  • Humulene – anti-inflammatory and anti-allergic activity

  • Bisabolol – supports irritated and inflamed skin states

  • Nerolidol – promotes tissue recovery

  • Myrcene – reduces inflammatory background and oxidative stress


Cannabinoids

  • CBD – immune-modulating background support

  • CBG – supports barrier function and neuroimmune balance

  • THC – may reduce acute inflammatory activity but can suppress immune tone when overstimulated


OG Lab strains

  • AC/DC CBD – soft daytime immune balancing

  • Banana Hammock RBX1 – deeper restorative background

  • Blueberry Bang Bang – suitable for skin sensitivity states

βœ“

Quick Answer

Cannabis modulates the immune system by regulating inflammation, impacting conditions like autoimmune disorders and allergies.

Want to read more?

Check out more articles, forum discussions, and cannabis education content